Rosalind Franklin - DNA | Ask A Biologist
Feminists have made much of the case of Rosalind Franklin, whose X-ray data were of Franklin's X-ray photos of DNA by Crick's friend Maurice Wilkins, the deputy director of the Franklin emerges from Maddox's biography as a highly able researcher with a warm and in many ways attractive personality. . LabQuizzes. James Watson was born in Chicago. He accumulated a lot of knowledge by reading the World Almanac, and won $ as a "Quiz Kid" on a popular radio program. rosalind franklin and maurice wilkins, james dewey watson, erwin Rosalind Franklin's graduate student - talks about Franklin's relationship with Maurice. British scientist Rosalind Franklin at work on the microscope. of DNA, along with fellow scientists James Watson and Maurice Wilkins. . They maintained their working relationship for more than 30 years. .. Take the Quiz.
How did it work? All of these questions were an important part of biology and many scientists were racing to find the answers. This portrait of Franklin was taken during her second visit to the United States. National Library of Medicine NIH The answer came from a group of scientists who were working on their own projects as well as a few who were on a giant scientific scavenger hunt.
James Watson and Francis Crick were two researchers who spent their time piecing together information that other scientists had published. They also spent time talking with scientists who were busy in their labs running experiments. One of these scientists was Rosalind Franklin 25 July — 16 April She was an expert in a technique called X-ray crystallography. Her work would hold the key to discovering the structure of DNAthe blueprint of life.
Her father did not like this at all, because it was not considered to be appropriate. Yet she was determined and stuck to her plan. It was not always easy though.
Her gender and her upper-class background made life difficult.Wilkins and Franklin (2016) IB Biology
It seems that some of her colleagues sneered at the way she spoke. On top of this women were not even allowed to enter the senior common room. This made her very angry, because many male colleagues had lunch there. However, none of this stopped Rosalind Franklin from making crucial contributions to science.
Contributions to Science Rosalind Franklin used a technique called X-ray crystallography to find out the 3D shape of molecules. She applied this technique to different samples. Early in her career she worked on carbon and coal. Later she started working on biological subjects.
She made major contributions to the discovery of the shape of DNA. After her work on this molecule, she also gave new insights into the first virus that was ever discovered: She thought the virus might be hollow and only consist of one strand of RNA. Although no proof existed at that time, she turned out to be right. Unfortunately, this was not confirmed until after her death.
15 Facts About Rosalind Franklin | Mental Floss
Two views of a tobacco mosaic virus. The side view left shows the helical shape of the virus. The top view right shows the opening in the center of the helix. Norrish recognized Franklin's potential but he was not very encouraging or supportive toward his female student.
CURA was a young organization and there was less formality on the way research had to be done. Franklin worked fairly independently, a situation that suited her. Franklin worked for CURA until and published a number of papers on the physical structure of coal. Franklin's next career move took her to Paris. An old friend introduced her to Marcel Mathieu who directed most of the research in France.
He was impressed with Franklin's work and offered her a job as a "chercheur" in the Laboratoire Central des Services Chimiques de l'Etat.
Crick, Watson, and Franklin
Here she learned X-ray diffraction techniques from Jacques Mering. InFranklin was offered a 3-year research scholarship at King's College in London. With her knowledge, Franklin was to set up and improve the X-ray crystallography unit at King's College.
Franklin arrived while Wilkins was away and on his return, Wilkins assumed that she was hired to be his assistant. It was a bad start to a relationship that never got any better.
Working with a student, Raymond Gosling, Franklin was able to get two sets of high-resolution photos of crystallized DNA fibers. She used two different fibers of DNA, one more highly hydrated than the other. From this she deduced the basic dimensions of DNA strands, and that the phosphates were on the outside of what was probably a helical structure. She presented her data at a lecture in King's College at which James Watson was in attendance.